NANOTEC-NSTDA developed a delivery system for reishi extract for cosmetic application. The technology was employed to create a facial serum ready to be released this month.

Dr. Thongchai Koobkokkruad, member of Nanolife and Cosmeceuticals Research Team revealed that the idea originated from the discussion between NANOTEC-NSTDA and Farm Kid Dee Company Limited to combine NANOTEC’s expertise in nano-scaled delivery platforms for precision delivery and controlled release of active ingredients with the company’s vision to create a high value product from reishi - a famous medicinal mushroom.

A joint project was set up to design an extraction method and a delivery system for reishi extract for cosmetic application with a research grant obtained from Innovative House Program managed by Thailand Research Fund in 2017. The team successfully developed niosomal delivery system for reishi extract. The niosome carrying reishi extract has a particle size ranging between 144.6 to 308.3 nm and 96.67% entrapment efficiency. The formulated noisome, trademarked as REISHOSOME, shows good stability and dispersion, no toxicity to fibroblast cell, and no skin irritation. Based on this technology, a facial serum containing REISHOSOME was developed. Irritation and efficacy tests have been performed to ensure product safety and performance. Tests conducted on volunteer subjects show that the product, named REISHURAL, has anti-wrinkle, skin brightening and moisturizing effects. Registration of REISHURAL facial serum has been submitted to the Thai FDA.

REISHURAL is manufactured at the Nanoparticles and Cosmetics Production Plant of NANOTEC-NSTDA and Farm Kid Dee will release the product this month. Sales of REISHURAL is projected to reach THB 30 million in the first three years. The company plans to expand the product line to include items such as sunscreen, as well as to supply reishi extract to other cosmetic manufacturers.

NANOTEC Executive Director Dr. Wannee Chinsirikul explained that NANOTEC’s main mission is to strive for excellence in nanotechnology research and development and to utilize research results to make socio-economic impact in accordance with the Bio-Circular-Green Economy (BCG) national policy. This research follows the BCG concept of applying science, technology and innovation to create additional value to resources and playing on the strength of Thailand which is its rich biological resources. “As a result, we are able to create a product in the booming beauty industry,” said Dr. Wannee.