Prince of Songkla University; Prince of Songkla University; National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC)
Type
Article
Source Title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN
0009-2363
Year
2007
Volume
55
Issue
4
Open Access
Bronze
Publisher
PHARMACEUTICAL SOC JAPAN
DOI
10.1248/cpb.55.1383
Format
PDF
Abstract
One new pyrone derivative, named penicillone (1), together with paxilline, pyrenocines A (2) and B (3) were isolated from the endophytic fungus Penicillium paxilli PSU-A71. The structures were elucidated by spectroscopic methods. Pyrenocine B (3) mildly inhibited the growth of Microsporum gypseum SH-MU-4 with a MIC value of 32 mu g/ml.
