Prince of Songkla University; National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC)
Type
Article
Source Title
CHEMICAL & PHARMACEUTICAL BULLETIN
ISSN
0009-2363
Year
2007
Volume
55
Issue
12
Open Access
Bronze
Publisher
PHARMACEUTICAL SOC JAPAN
DOI
10.1248/cpb.55.1647
Format
PDF
Abstract
Chemical investigation of the wood-decayed fungus Xylaria sp. BCC 9653 has led to the isolation of a new methyl aminobenzoate (1) together with eleven known compounds. The structures were established by analysis of spectroscopic data. Cytochalasin D (2), one of the known metabolites, exhibited potent cytotoxicity against African green monkey kidney fibroblast (Vero) cells with an IC50 value of 0.19 mu M.
