Prevalence of Mycobacterium tuberculosis Complex among Wild Rhesus Macaques and 2 Subspecies of Long-Tailed Macaques Thailand 2018-2022
Author
Meesawat S. Warit S. Hamada Y. Malaivijitnond S.
Affiliations
Chulalongkorn University Faculty of Science Bangkok Thailand; National Science and Technology Development Agency Pathumthani Thailand; Chulalongkorn University National Primate Research Center of Thailand Saraburi Thailand
Type
Article
Source Title
Emerging Infectious Diseases
ISSN
10806040
Year
2023
Volume
29
Issue
3
Page
551-560
Open Access
All Open Access Gold Green
Publisher
Centers for Disease Control and Prevention (CDC)
DOI
10.3201/eid2903.221486
Abstract
We identified tuberculosis in 1 836 macaques from 6 wild rhesus (Macaca mulatta) 23 common long-tailed (M. fascicularis fascicularis) and 6 Burmese long-tailed (M. fascicularis aurea) macaque populations in Thailand. We captured anesthetized and collected throat buccal and rectal swab specimens from the macaques. We screened swabs for Mycobacterium tuberculosis complex (MTBC) using insertion sequence 6110-specific nested PCR. We found higher MTBC prevalence at both population and individual levels among M. mulatta than M. fascicularis fascicularis macaques; all 3 M. fascicularis aurea macaque populations were positive for tuberculosis. We found that throat swab specimens provided the best sample medium for detecting MTBC. Our results showed no difference in MTBC prevalence between male and female animals but a higher percentage of adults were infected than subadults and juveniles. Although we detected no association between frequency of human-macaque interaction and MTBC prevalence bidirectional zoonotic transmission should be considered a possible public health concern. ? 2023 Centers for Disease Control and Prevention (CDC). All rights reserved.
