Patulin-imprinted origami 3D-ePAD based on graphene screen-printed electrode modified with Mn朲nS quantum dot coated with a molecularly imprinted polymer
Patulin-imprinted origami 3D-ePAD based on graphene screen-printed electrode modified with Mn朲nS quantum dot coated with a molecularly imprinted polymer
Author
Sodkrathok P. Karuwan C. Kamsong W. Tuantranont A. Amatatongchai M.
Affiliations
Department of Chemistry and Center of Excellence for Innovation in Chemistry Faculty of Science Ubon Ratchathani University Ubon Ratchathani 34190 Thailand; Graphene and Printed Electronics for Dual-Use Applications Research Division (GPERD) National Science and Technology Development Agency (NSTDA) Pathum Thani 12120 Thailand
Type
Article
Source Title
Talanta
ISSN
399140
Year
2023
Volume
262
Open Access
All Open Access Bronze
Publisher
Elsevier B.V.
DOI
10.1016/j.talanta.2023.124695
Abstract
We developed a novel compact three-dimensional electrochemical paper-based analytical device (3D-ePAD) for patulin (PT) determination. The selective and sensitive PT-imprinted Origami 3D-ePAD was constructed based on a graphene screen-printed electrode modified with manganese-zinc sulfide quantum dots coated with patulin imprinted polymer (Mn朲nS QDs@PT-MIP/GSPE). The Mn朲nS QDs@PT-MIP was synthesized using 2-oxindole as the template methacrylic acid (MAA) as a monomer N N?-(1 2-dihydroxyethylene) bis (acrylamide) (DHEBA) as cross-linker and 2 2?-azobis (2-methylpropionitrile) (AIBN) as initiator respectively. The Origami 3D-ePAD was designed with hydrophobic barrier layers formed on filter paper to provide three-dimensional circular reservoirs and assembled electrodes. The synthesized Mn朲nS QDs@PT-MIP was quickly loaded on the electrode surface by mixing with graphene ink and then screen-printing on the paper. The PT-imprinted sensor provides the greatest enhancement in redox response and electrocatalytic activity which we attributed to synergetic effects. This arose from an excellent electrocatalytic activity and good electrical conductivity of Mn朲nS QDs@PT-MIP which improved electron transfer between PT and the electrode surface. Under the optimized DPV conditions a well-defined PT oxidation peak appears at +0.15 V (vs Ag/AgCl) using 0.1 M of phosphate buffer (pH 6.5) containing 5 mM K3Fe(CN)6 as the supporting electrolyte. Our developed PT imprinted Origami 3D-ePAD revealed excellent linear dynamic ranges of 0.001� ?M with a detection limit of 0.2 nM. Detection performance indicated that our Origami 3D-ePAD possesses outstanding detection performance from fruits and CRM in terms of high accuracy (%Error for inter-day is 1.11%) and precision (%RSD less than 4.1%). Therefore the proposed method is well-suited as an alternative platform for ready-to-use sensors in food safety. The imprinted Origami 3D-ePAD is an excellent disposable device with a simple cost-effective and fast analysis and it is ready to use for determining patulin in actual samples. ? 2023 Elsevier B.V.
