Thammasat University; National Science & Technology Development Agency - Thailand; Mahidol University; Ministry of Public Health - Thailand; Khon Kaen University
Type
Article
Source Title
SCIENTIFIC REPORTS
Year
2022
Volume
12
Issue
1
Open Access
gold, Green Published
Publisher
NATURE PORTFOLIO
DOI
10.1038/s41598-022-05898-1
Format
PDF
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant causative agent of hospital-acquired infections. We characterized MRSA isolated from August 2012 to July 2015 from Thammasat University Hospital. Genotypic characterization of MRSA SCCmec type II and III isolates were scrutinized by whole genome sequencing (WGS). The WGS data revealed that the MRSA SCCmec type II isolates belonged to ST764 previously reported mainly in Japan. All of tested isolates contained ACME Type II ', SaPIn2, SaPIn3, seb, interrupted SA1320, and had a virulence gene profile similar to Japan MRSA ST764. Rigorous surveillance of MRSA strains is imperative in Thailand to arrest its potential spread.
National Research Council of Thailand [94248/2557A10602093, 111854/2558A10602034]; Faculty of Medicine, Thammasat University, Thailand [2-07-2563]; National Science and Technology Development Agency [JRA-CO-2564-13515]; Research Group in multidrug resistant bacteria and the antimicrobial herbal extracts, Faculty of Medicine, Thammasat University [RG2564]
