National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC)
Type
Article
Source Title
JOURNAL OF ANTIBIOTICS
ISSN
0021-8820
Year
2007
Volume
60
Issue
8
Open Access
Bronze
Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI
10.1038/ja.2007.98
Format
PDF
Abstract
A new linear polyester, menisporopsin B, along with the known macrocyclic polyester, menisporopsin A, was isolated from the seed fungus Menisporopsis theobromae BCC 4162. The structure of menisposopsin B was addressed primarily by spectroscopic analyses, and the stereochemistry was established by chemical correlation. Menisporopsin B exhibited antimalarial activity with an IC50 value of 1.0 mu g/ml.
