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MEMS-Based Dual-Axes Confocal Microendoscopy
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Metadata
Document Title
MEMS-Based Dual-Axes Confocal Microendoscopy
Author
Piyawattanametha W, Wang TD
Name from Authors Collection
Affiliations
National Science & Technology Development Agency - Thailand; National Electronics & Computer Technology Center (NECTEC); Chulalongkorn University; Stanford University; Stanford University; Stanford University; Stanford University; Stanford University; University of Michigan System; University of Michigan; University of Michigan System; University of Michigan
Type
Article
Source Title
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
Year
2010
Volume
16
Issue
4
Page
804-814
Open Access
Green Accepted
Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI
10.1109/JSTQE.2009.2032785
Format
Abstract
In this paper, we demonstrate a miniature, near-infrared microscope (lambda = 785 nm) that uses a novel dual-axes confocal architecture. Scalability is achieved with postobjective scanning, and a microelectromechanical systems mirror provide real-time (>4 Hz) in vivo imaging. This instrument can achieve subcellular resolution with deep tissue penetration and large field of view. An endoscope-compatible version can image digestive tract epithelium to guide tissue biopsy and monitor therapy.
Keyword
Fluorescence | imaging | medical diagnosis | microelectromechanical devices | microscopy | mirrors
Industrial Classification
Knowledge Taxonomy Level 1
Knowledge Taxonomy Level 2
Knowledge Taxonomy Level 3
Funding Sponsor
National Institutes of Health [U54 CA105296, R33 CA109988, K08 DK67618, P50 CA93990, U54 CA136429]; NATIONAL CANCER INSTITUTE [U54CA105296, R01CA142750, P50CA093990, U54CA136429, R33CA109988] Funding Source: NIH RePORTER; NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [K08DK067618] Funding Source: NIH RePORTER
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Publication Source
WOS