Mahidol University; Mahidol University; National Science & Technology Development Agency - Thailand
Type
Article
Source Title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN
0066-4804
Year
2007
Volume
51
Issue
9
Open Access
Green Published
Publisher
AMER SOC MICROBIOLOGY
DOI
10.1128/AAC.01310-06
Format
PDF
Abstract
The in vitro activities of cloxyquin (5-chloroquinolin-8-ol) against 9 standard strains and 150 clinical isolates of Mycobacterium tuberculosis were studied. The MICs ranged from 0.062 to 0.25 mu g/ml. The MIC,, and MIC,0 were 0.125 and 0.25 mu g/ml, respectively. These indicate that cloxyquin exhibited good antituberculosis activity, even for multidrug-resistant isolates.
