University of Wollongong; National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC)
Type
Article
Source Title
LETTERS IN DRUG DESIGN & DISCOVERY
ISSN
1570-1808
Year
2008
Volume
5
Open Access
Green Submitted
Publisher
BENTHAM SCIENCE PUBL LTD
DOI
10.2174/157018008784619843
Format
PDF
Abstract
A series of 2,4- and 4,6-diaminopyrimidines were prepared and evaluated for their in vitro antimalarial activity. Of the 12 compounds tested 7 showed reasonable activity with 1 having a sub-micromolar IC50.
