Chiang Mai University; Chiang Mai University; Chiang Mai University; Mae Fah Luang University; National Science & Technology Development Agency - Thailand; National Center Genetic Engineering & Biotechnology (BIOTEC); University of Wollongong; Chiang Mai University
Type
Article
Source Title
NATURAL PRODUCT RESEARCH
ISSN
1478-6419
Year
2020
Volume
34
Issue
10
Page
1394-1398
Open Access
Green Submitted
Publisher
TAYLOR & FRANCIS LTD
DOI
10.1080/14786419.2018.1512990
Format
PDF
Abstract
A new 2-arylbenzofuran, spathobenzofuran (1), together with ten known compounds including a 2-arylbenzofuran, three pterocarpans and six isoflavones were isolated from the acetone crude extract of the stems of Spatholobus parviflorus. All compounds were characterised by spectroscopic methods. Compound 4 was active (MIC 8 mu g/mL) against Gram-negative Pseudomonas aeruginosa TISTR 781 while compound 2 had modest activity against Gram-positive Staphylococcus aureus TISTR 1466 with a MIC value of 16 mu g/mL. All isolated compounds showed no cytotoxicity against Vero and KB cells.
