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Investigations of brain-wide functional and structural networks of dopaminergic and CamKII?-positive neurons in VTA with DREADD-fMRI and neurotropic virus tracing technologies
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Metadata
Document Title
Investigations of brain-wide functional and structural networks of dopaminergic and CamKII?-positive neurons in VTA with DREADD-fMRI and neurotropic virus tracing technologies
Author
Zheng N., Gui Z., Liu X., Wu Y., Wang H., Cai A., Wu J., Li X., Kaewborisuth C., Zhang Z., Wang Q., Manyande A., Xu F., Wang J.
Affiliations
Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics, Wuhan, 430071, China; University of Chinese Academy of Sciences, Beijing, 100049, China; Department of Anaesthesia and Intensive Care, Peter Hung Pain Research Institute, The Chinese University of Hong Kong, SAR, Hong Kong; Shenzhen Key Laboratory of Viral Vectors for Biomedicine, Key Laboratory of Quality Control Technology for Virus-Based Therapeutics, Guangdong Provincial Medical Products Administration, NMPA Key Laboratory for Research and Evaluation of Viral Vector Technology in Cell and Gene Therapy Medicinal Products, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China; College of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fujian, Fuzhou, China; Virology and Cell Technology Research Team, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathumthani, 12120, Thailand; Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School for Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; School of Human and Social Sciences, University of West London, Middlesex, TW8 9GA, United Kingdom; Institute of Neuroscience and Brain Diseases, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Hubei, Xiangyang, China
Type
Article
Source Title
Journal of Translational Medicine
ISSN
14795876
Year
2023
Volume
21
Issue
1
Open Access
All Open Access|| Gold
Publisher
BioMed Central Ltd
DOI
10.1186/s12967-023-04362-6
Keyword
animal | animal cell | animal experiment | animal tissue | Animals | Article | BOLD signal | brain | brain function | brain region | calcium calmodulin dependent protein kinase II | comparative study | controlled study | diagnostic imaging | Dopamine | dopaminergic nerve cell | Dopaminergic Neurons | functional magnetic resonance imaging | insula | Magnetic resonance imaging | male | nerve cell | nerve cell network | neurotropic virus | nonhuman | nuclear magnetic resonance imaging | physiology | procedures | Rat | Rats | signal transduction | structure activity relation | tracer | transgenic rat | Ventral Tegmental Area | ventral tegmentum
Industrial Classification
Knowledge Taxonomy Level 1
Knowledge Taxonomy Level 2
Knowledge Taxonomy Level 3
License
CC BY
Rights
Authors
Publication Source
Scopus