National Science and Technology Development Agency : NSTDA - Thailand

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Climate change has affected disease outbreak trends. Various germs have mutated and become resistant to drugs.  There are newly emerging diseases and re-emerging infectious diseases.  There are still no treatments to cure or control many chronic diseases.  In Thailand, besides preparing for outbreaks, the country also needs to be prepared for public health services for people with disabilities and the Elderly whose numbers are likely to climb.

NSTDA is aware of these issues; therefore, focuses on using science, technology and innovations to increase medical care efficiency in preventing diseases, treating and rehabilitating patients as well as on preparing for the changes of the health situation in the future.  This is achieved through 3 research programs:

The Newly Emerging Disease - Re-emerging Disease Program
The program aims to create knowledge and products that can promptly solve problems related to and address newly emerging and re-emerging diseases as well as increasing research capability so that the country is self reliant and stable. Key operation plans include:
(1) Doing R&D work to create dengue vaccine prototypes to be tested in humans by 2016, focusing on improving research to create dengue serotype 2 vaccines and test tetravalent vaccines in monkeys.
(2) Doing R&D work to create anti-malaria substance prototypes to be tested in small lab animals and focusing on research on key antigens of the P. falciparum and the P. vivax.
(3) Doing R&D work to increase capability of outbreak prediction systems, using mathematical models.

The Genotype Technology Program
The program uses genotype-phenotype associations to develop predictive, preventive and personalized medicinal technologies for chronic diseases and geriatric diseases such as osteoporosis, diabetes and kidney disease.  In addition, there is also R&D work that leads to pharmacogenetic test kits or testing technologies to be used to test drug allergies in Thais.  The focus is on preventing severe drug allergic reactions (SJS/TENS) and allergic reactions to expensive drugs that are used for a prolonged period such as cancer drugs and antipsychotic drugs.

Assistive Devices and Technologies for People with Disabilities and The Elderly Program
The program focuses on R&D work on the designing and engineering of assistive technologies, devices and equipment for protecting, monitoring, rehabilitating and improving the quality of life of people with disabilities and the Elderly. Key operation plans include:

(1) Prevention/screening, which focuses on R&D work to create devices that help solve the problem of falling and prevent falling in the Elderly.  This will also help solve the problem of a shortage of geriatric care personnel.
(2) Rehabilitation which focuses on R&D work to create rehabilitation equipment for people with disabilities.  The equipment produced is equivalent to exported items in terms of efficiency but is reasonably priced.
(3) Assistive technology which focuses on R&D work to create assistive equipment and technology to help increase the capabilities of people with disabilities and the Elderly so that they can make a living similar to people with no disability. 

December 09, 2015

LAMP-LFD assay for malaria parasite detection

Malaria is largely a preventable and curable disease. However, a delay or an inappropriate treatment can result in serious adverse outcomes for patient. Rapid, simple and cost-effective diagnostic tests that can be easily adapted and rapidly scaled-up at the field or community levels are needed. BIOTEC researchers have developed an…
August 26, 2014

Discovery of a novel redox switch of PfSHMT: A challenge for antimalarial drug design

The rapid rise in drug-resistant malaria compromises the use of current anti-malarial drugs. Plasmodium falciparum serine hydroxymethyltransferase (PfSHMT), an enzyme in the dTMP synthesis cycle, is a potential target for the development of new drug because inhibition of its expression or function has been shown to be lethal to the…
September 19, 2013

Serotyping-NS1 ELISA for detection of dengue NS1 protein and serotyping of dengue virus simultaneously

Dengue is caused by four closely related viruses, dengue serotypes 1 – 4. Severe dengue hemorrhagic fever is associated with a secondary response to an infection by different dengue serotypes.  Determination of dengue serotypes in current and previous epidemics is also crucial in being able to predict the severity of…
November 27, 2012

Sensing Diabetic Breathe

Diabetes is one of the top 5 chronic non-communicable diseases in Thailand and is directly related to the growing consumption of cheap, processed sugar among the population.  . About 3.5 million Thais have been diagnosed with diabetes, and this number is expected to grow close to ten million in the…
August 08, 2012

First Thai-made Dental CT (DentiScan)

Dental CT (DentiScan), first Thai-made prototype of computerized X-ray machine for dental treatment, is a product of a collaboration between MTEC (National Metal and Materials Technology Center) and NECTEC (National Electronics and Computer Technology Center) for their hardware and software development, respectively.  The machine has gone through a clinical trial…
July 06, 2012

Three research funding agencies in Thailand and the UK join hands to promote biotechnology research

The Thailand Research Fund (TRF) and The National Science and Technology Development Agency (NSTDA) signed an MOU with the Biotechnology and Biological Sciences Research Council (BBSRC) of the UK for collaboration on research and human resources development in the field of biotechnology and biological sciences with focuses on three research…
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